1 March 2018

Recent infection testing algorithm technical update — Applications for HIV surveillance and programme monitoring

This technical update provides public health officials with guidance on applying HIV incidence assays and testing algorithms for recent HIV infection in order to monitor the HIV epidemic and assess the impact of interventions. A major theme of this update is the importance of calibrating two of the key performance characteristics of recent testing infections algorithms—mean duration of recent infection and false recent ratio— to account for the context in which the testing is being done. This technical update also describes several emerging use cases in the application of recent infection testing algorithms and tests, including those for individual-level use. A final section on further research directions is provided to highlight areas that still require investigation.